Design of solid lipid nanoparticles for caffeine topical administration

Safranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications

Objective(s): In the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. Materials and Methods:Series of SLN were prepared using glyceryl monostearate, Tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (HPH) methods. SLN formulations were characterized ...

Exploring Solid Lipid Nanoparticles for Intranasal Administration of Streptomycin

Streptomycin, the foremost class of drugs called aminoglycosides to be discovered is the only antibiotic remedy for tuberculosis. Streptomycin cannot be given orally, but must be administered by regular intramuscular injections as it is reported to have unreliable absorption throughout the GIT. Further to this, its use in cerebral tuberculosis is minimal as it does not cross the blood brain bar...

Zaltoprofen Loaded Solid Lipid Nanoparticles for Topical Delivery: Formulation Design, In Vitro and Ex Vivo Evaluation

The number of new pharmaceutical compounds with poor aqueous solubility has grown steadily over the last two decades due to the progress in discovery technologies, e.g. high throughput and combinatorial screening tools, during lead development and optimization phase. Most of these compounds are mainly categorized as bio pharmaceutics classification system (BCS) class II for which their oral abs...

safranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications

objective(s): in the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (sln)-safranal formulations were evaluated. materials and methods:series of sln were prepared using glyceryl monostearate, tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (hph) methods. sln formulations were characterized ...

preparation and stability evaluation of urea-loaded solid lipid nanoparticles for topical application.